A groundbreaking new book, Understanding ME/CFS & Strategies for Healing, has been released, revealing cutting-edge research into Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and Long Covid. Written by Irish ME/CFS patient and advocate Patrick Ussher, the book presents a comprehensive summary of a landmark research model developed by German scientists Prof. Carmen Scheibenbogen and Prof. Klaus Wirth. Their research proposes a “unifying model” of ME/CFS and Long Covid, showing how many previously disconnected findings are interconnected in a single disease mechanism.
The model describes a cascade of vicious physiological cycles – including autoimmunity, vascular dysfunction, and cellular energy failure – that could finally explain the complex symptoms experienced by millions worldwide. According to Ussher, this breakthrough “could demystify an illness that has perplexed doctors and researchers for decades.”
One of the most significant aspects of the book is its introduction of a potential medication for ME/CFS and Long Covid. Mitodicure, a compound being developed by Prof. Wirth, targets the core cellular bottleneck believed to lie at the heart of both conditions. While funding is still being sought for clinical trials, Mitodicure is intended, in principle, to be curative.
Prof. Wirth, who also wrote the book’s foreword, describes his own work on ME/CFS and the proposed mechanism of action underlying his medication. The book also offers practical treatment strategies for improving quality of life, all grounded in emerging research and patient insights.
ME/CFS and Long Covid are estimated to affect over 80 million people globally, yet remain under-researched, under-treated, and often misunderstood. Understanding ME/CFS & Strategies for Healing has already been featured in The Irish Times and reviewed in The Medical Independent, one of Ireland’s leading publications for healthcare professionals. Additionally, a YouTube interview with Prof. Klaus Wirth, conducted by Ussher, is now available, where Wirth discusses both the research and the development of Mitodicure.
In an interview with The Medical Independent, Ussher stated, “Understanding ME/CFS & Strategies for Healing offers one patient’s view through the long grass which has grown around an illness badly served by medical dogmatists, and it is a view which readers have much to learn from. It could herald a sea change in how ME/CFS is researched, managed, treated… and, just possibly, cured.”
Journalists interested in receiving a review copy or arranging an interview with Patrick Ussher and/or Prof. Klaus Wirth are warmly invited to get in touch via the contact details provided.
About Patrick Ussher
Patrick Ussher has lived with ME/CFS for seven years. He runs a YouTube channel dedicated to distilling the latest research and treatment strategies for fellow patients, and has written regularly for patient publications and given talks for the Irish ME Trust. In addition to his advocacy work, he is also a composer of contemporary classical music and the author of several books on Stoic philosophy. For more information, visit his personal website.

Derick is an experienced reporter having held multiple senior roles for large publishers across Europe. Specialist subjects include small business and financial emerging markets.