Research indicates that microbiome enterotypes and prenatal hormones may be involved in the development of chronic diseases.

DervalResearch, a certified B Corp, have revealed the findings of a research study conducted on the combined effects of people’s microbiomal and hormonal makeup with regards to proneness to chronic disorders and food allergies.

The microbiome, including those found in the gut, mouth and skin, is composed of a variety of bacteria, fungi and viruses. Through thousands of measurements and DNA sequencing performed across the globe, three main microbiome enterotypes have emerged (E1-Bacteroides, E2-Prevotella and E3-Ruminococcus).

The microbiome enterotypes were identified via fecal Next Generation DNA-sequencing, and the prenatal hormones were evaluated with the digit ratio technique. Subjects listed the chronic disorders they suffered from and noted their eating behaviour and preferences.

The findings of the research were presented at the Physiology in Focus 2023 conference in Tallinn, Estonia. Prof. Diana Derval, Chief Investigator of DervalResearch, highlighted: “Subjects with a Bacteroides microbiome enterotype (E1) and/or more influenced by prenatal testosterone presented a higher prevalence of chronic disorders, including food allergies.”

The reported chronic diseases included atopic dermatitis, asthma, anorexia nervosa, obesity and osteoporosis. The reported food allergies were related to cereals and milk, and the avoidance of sensitising foods was associated with an improved health perception.

To help evaluate people’s microbiome, DervalResearch have designed Microbiot, an intelligent web-based bot available on their website or by scanning the QR code. However, a laboratory analysis is still needed for 100% accuracy.

This research has the potential to open new prevention avenues in the field of chronic diseases and food allergies, with targeted health and nutrition plans based on microbiome enterotype and hormonal fingerprint being the key to a stronger immune system.

Derick is an experienced reporter having held multiple senior roles for large publishers across Europe. Specialist subjects include small business and financial emerging markets.

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